MYC是致癌基因，编码蛋白是一种转录因子，其调节参与多种细胞过程的基因的表达，包括增殖，分化和凋亡。MYC编码的转录因子与MAX蛋白形成异二聚体，以控制数千个基因的转录。MYC通过诱导增殖，抑制细胞周期退出，刺激血管形成和增强基因组不稳定性来促进肿瘤发生。MYC通过多种机制在癌症中被激活，包括染色体易位（通常与血癌相关，并与组成型过表达相关），以及基因组扩增和过表达。MYC基因突变的发生频率不如扩增和易位。

MYC gene encodes a transcription factor that heterodimerizes with the protein MAX to control the transcription of thousands of genes. MYC promotes tumorigenesis by inducing proliferation, inhibiting exit from the cell cycle, stimulating vascularization and enhancing genomic instability. MYC becomes activated in cancers through a variety of mechanisms, including chromosomal translocations (typically associated with blood cancers, and associated with constitutive over-expression), as well as genomic amplification and overexpression. Mutations in the MYC gene occur, but are less frequent than amplification and translocation.

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