IL-8编码一种趋化因子,是CXC趋化因子家族的成员,并且是炎症反应的主要介质。IL-8可吸引中性粒细胞,嗜碱性粒细胞和T细胞,但不吸引单核细胞。其还涉及中性粒细胞活化,响应于炎症刺激而从几种类型细胞中释放。
Interleukin-8 (IL8) is a member of the CXC chemokine family These small basic heparin-binding proteins are proinflammatory and primarily mediate the activation and migration of neutrophils into tissue from peripheral blood.
GeneCards OncoKB My Cancer Genome