FANCG
小结
FANCG编码蛋白为参与DNA损伤修复的FANC的一个组分。范可尼贫血是一种常染色体隐性遗传疾病，其特征是细胞遗传学不稳定，对DNA交联剂过敏，染色体断裂增加和DNA修复缺陷。 Fanconi贫血互补组的成员不具有序列相似性;FANCG的种系突变与范可尼贫血有关，易患乳腺癌。
FANCG, Fanconi anemia, complementation group G, is a member of the Fanconi anemia core complex, which plays a role in DNA repair. Germline FANCG mutations are associated with Fanconi anemia, which involves predisposition to various cancers.